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Abstract #1104

Sensitivity and Spatial Specificity of Multiple Phase-Cycled Pass-Band BSSFP FMRI at 9.4T

Sung-Hong Park1,2, Tae Kim1, Ping Wang1, Timothy Q. Duong2, Seong-Gi Kim1

1Radiology, University of Pittsburgh, Pittsburgh, PA, United States; 2Research Imaging Institute, Ophthalmology/Radiology, University of Texas Health Science Center at San Antonio, San Antonio, TX, United States

We performed high-resolution pass-band bSSFP fMRI at multiple phase cycling angles on rat brain at 9.4T. Activation foci in fMRI maps shifted as a function of phase cycling angle and the location of the foci was correlated with hyperintense regions in corresponding baseline transition-band bSSFP, some of which were also correlated with cortical surface veins or intracortical veins. The results indicated that there is spatial heterogeneity in signal sources (T2 or T2*) of pass band bSSFP fMRI. Baseline transition band bSSFP could be used to predict outcomes of corresponding pass-band bSSFP fMRI maps.