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Abstract #1134

Calibrated FMRI During a Cognitive Stroop Task in the Aging Brain

Rafat Saeed Mohtasib1,2, Vanessa Sluming1,2, Laura Parkes1,3

1Magnetic Resonance and Image Analysis Research Centre (MARIARC), The University of Liverpool, Liverpool, United Kingdom; 2Medical Imaging Department, The University of Liverpool, United Kingdom; 3Imaging Science and Biomedical Engineering, School of Cancer and Imaging Sciences, The University of Manchester, United Kingdom

Calibrated fMRI is a new technique that allows quantitative estimates of the relative changes in cerebral metabolic rate of oxygen (CMRO2) and cerebral blood flow (CBF) that accompany neural activation. In this research we extend our previous work to study changes in neurovascular coupling over an age range during a cognitive Stroop task.