Salem
Boussida1, Amidou Traore2, Jean-Pierre Renou2,
Franck Durif3
1INRA, UR370 QuaPA/NMR plateforme, Centre
Clermont-Ferrand/Theix, F-63122 Saint Gens Champanelle, France; 2INRA,
UR370 QuaPA/NMR plateforme, Centre
Clermont-Ferrand/Theix, F-63122 Saint
Gens Champanelle, France; 3CHU Clermont-Ferrand, Service de
Neurologie, Clermont-Ferrand, F-63001, France.
Combination
of blood oxygen level-dependent functional magnetic resonance imaging (BOLD
fMRI) and electrical hindpaw stimulation has been used as a standard model to
study the somatosensory pathway and brain rehabilitation in rats. In the
present study, we examined the feasibility of performing BOLD fMRI
experiments on rat to investigate the activity of the basal ganglia
(BG)-cortex circuit associated to hindpaw sensitive stimulation. These
findings will have relevance in the fMRI studies dealing with physiopathology
of neurodegenerative diseases such as Parkinson
Keywords