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Abstract #1282

Non-Selective Double Inversion Recovery Pre-Pulse for Flow-Independent Black Blood Myocardial Viability Imaging

Sarah Anne Peel1, Christian Jansen1, Geraint Morton1, Simon Duckett1, Tobias Schaeffter1, Ren M. Botnar1

1Division of Imaging Sciences, King's College London, London, United Kingdom

MRI late gadolinium enhancement using the inversion-recovery sequence is the current gold standard for the assessment of myocardial viability. Although it achieves high contrast between infarct and normal myocardium, there is often poor infarct-to-blood contrast. We sought to improve infarct-to-blood contrast using a novel non-selective double inversion technique that provides flow-independent signal suppression over a wide user-defined T1-range. Simulations and phantom studies demonstrate excellent tissue suppression over a wide T1-range. Preliminary patient data show an improvement in infarct-to-blood CNR. This technique facilitates detection of sub-endocardial defects and has potential for more accurate quantification of infarct size and transmurality.