Abstract #1310

Magic Angle Spinning MRS for Identifying Biomarkers of Perfusion Preservation of Human Hearts After 12 Hour Storage

Michael L. Cobert¹, Matthias Peltz¹, Matthew E. Merritt², LaShondra M. West¹, Larry Ammann³, Michael E. Jessen¹

¹Cardiovascular and Thoracic Surgery, University of Texas Southwestern Medical Center at Dallas, Dallas, TX, United States; ²Advanced Imaging Research Center, University of Texas Southwestern Medical Center at Dallas, Dallas, TX, United States; ³Mathematics, University of Texas at Dallas, Dallas, TX, United States

Perfusion preservation of donor hearts appears promising for extending the donor ischemic interval and utilization of extended donors. A major risk of using so-called marginal donors is predicting the viability of the graft. The current study utilizes proton magic angle spinning spectroscopy to determine biomarkers of perfusion preservation. These data suggest MAS MRS may be useful for determining heart function prior to implantation