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Abstract #1344

Reproducibility of Pulse Wave Velocity Measurements with Phase Contrast Magnetic Resonance and Applanation Tonometry

Jonathan D. Suever1, David Huneycutt2, Enrique Rojas-Campos3, Francesca Cardarelli3, Sam Fielden2, Arthur Stillman, 2,3, Paolo Raggi3, John N. Oshinski, 12

1Biomedical Engineering, Georgia Institute of Technology / Emory University, Atlanta, GA, United States; 2Radiology, Emory University School of Medicine, Atlanta, GA, United States; 3Cardiology, Emory University School of Medicine, Atlanta, GA, United States

Increased aortic pulse wave velocity (PWV) due to arterial stiffening is commonly seen in patients with hypertension. Clinically, applanation tonomtery is used to measure PWV; however, we have developed a new method that uses PCMR combined with cross-correlation analysis. The purpose of this study was to compare the reproducibility of cross-correlation and applanation tonometry in normals and patients. In normal volunteers, the reproducibility of cross-correlation technique was better than applanation tonometry. In patients, cross-correlation and applanation tonometry measurements were not statistically different.