High Temporal and Spatial Resolution 3D CE-MRA of the Whole Brain

Clifton R. Haider¹, Josh Damon Trzasko¹, Eric A. Borisch¹, Norbert G. Campeau¹, Petrice M. Mostardi¹, John Huston¹, Armando Manduca¹, Stephen J. Riederer¹

The purpose of this work is to demonstrate the implementation of a dynamic MRA technique using 12x 2D SENSE accelerated Cartesian Acquisition with Projection-Reconstruction-like sampling for angiographic imaging of the brain, with 1 sec frame time and 3 sec temporal footprint, sufficient to resolve arterio-venous transit of cerebral blood flow. Additional post-processing with a non-convex compressive sensing reconstruction is also presented, resulting in further improvement of angiographic image quality, from removal of non-uniform noise amplification.