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Abstract #1377

T1 Contrast of MPRAGE in Carotid Plaque Imaging

Yiu-Cho Chung1, Michael Jerosch-Herold2, Ravi T. Seethamraju3, Peter Libby4, Marcelo Di Carli5, Raymond Kwong6

1Siemens Medical Solutions USA, Inc., Columbus, OH, United States; 2Radiology, Brigham and Women's Hospital, MA, United States; 3Siemens Medical Solutions USA, Inc., MA, United States; 4Cardiovascular Medicine, Brigham and Women's Hospital, MA, United States; 5Nuclear Medicine, Brigham and Women's Hospital, MA, United States; 6Cardiovascular Imaging, Brigham and Women's Hospital, MA, United States


MPRAGE has excellent T1 contrast and is useful for thrombus imaging. Though blood is usually suppressed in vessel wall imaging, nonzero blood signal may be useful in depicting blood and vessel wall. By setting TI longer than the blood null time, MPRAGE can provide good contrast between blood and vessel wall due to their intrinsic T1 difference. In a small patient cohort, we used such approach for MPRAGE, and compared the images with T2w-SPACE. We found that the grey blood MPRAGE can provide information about the plaque and lumen that was not obvious in dark blood images.

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