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Abstract #1414

High-Resolution Ex Vivo Magnetic Resonance Angiography: A Feasibility Study on Biological and Medical Tissues

Anne S. Rasmussen1, Henrik Lauridsen2, Bjarke G. Jensen2, Steen Fjord Pedersen1, Tobias Wang2, Niels Uldbjerg3, Michael Pedersen1

1MR-research Centre Aarhus University Hospital, Aarhus, Denmark; 2Department of Biology, Aarhus University, Aarhus, Denmark; 3Department of Gynaecology and Obstetrics, Aarhus University Hospital, Aarhus, Denmark

In vivo angiography is often used in biomedical science. Ex vivo angiography of excised organs or whole body is however rarely used due to the lack of appropriate contrast solutions capable of entering and staying in the vasculature after amputation or death. This study aims to develop contrast solutions and methods for ex vivo MRA and CTA. Two solutions were produced and used for MRA and CTA in four different species. MRA was found to have an advantage to CTA in situations where blood vessels were in close proximity to bones that can interfere with the signal in CTA.