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Abstract #1560

Fractional Anisotropy in Various White and Gray Matter Regions in Adulthood. Dependence on Age and Comparison of Two DTI Sequences

Ji Keller1,2, Aaron Michael Rulseh1, Michael Syka1, Josef Vymazal1

1Nemocnice Na Homolce, Prague, Czech Republic; 23rd Faculty of Medicine, Charles University in Prague, Prague, Czech Republic

We measured FA in white and gray matter regions using two different DTI sequences (12 and 30 directions) in 23 healthy adult volunteers A number of white and gray matter regions were selected including basal ganglia and corpus callosum. The gray matter results were correlated with expected iron concentration. We detected a significant correlation between age and FA for both DTI sequences in the rostrum of the corpus callosum, anterior internal capsule and the pyramidal tract. A significant difference in FA between DTI sequences was detected in the basal ganglia where correlation between iron amount and FA was found.