Fractional Anisotropy in Various White and Gray Matter Regions in Adulthood. Dependence on Age and Comparison of Two DTI Sequences

Ji Keller^1,2, Aaron Michael Rulseh¹, Michael Syka¹, Josef Vymazal¹

We measured FA in white and gray matter regions using two different DTI sequences (12 and 30 directions) in 23 healthy adult volunteers A number of white and gray matter regions were selected including basal ganglia and corpus callosum. The gray matter results were correlated with expected iron concentration. We detected a significant correlation between age and FA for both DTI sequences in the rostrum of the corpus callosum, anterior internal capsule and the pyramidal tract. A significant difference in FA between DTI sequences was detected in the basal ganglia where correlation between iron amount and FA was found.