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Abstract #1648

SPM Normalisation Toolbox for Diffusion Weighted Images

Volkmar H. Glauche1, Siawoosh Mohammadi2, Michael Deppe2

1Department of Neurology, University Hospital Freiburg, Freiburg, Germany; 2Department of Neurology, University of Muenster, Germany

The toolbox implements normalisation strategies to prepare data for VBM-style voxel-based statistics of FA images (FA-VBS) in SPM. It provides a convenient interface to spatially normalise DWI datasets even if no additional anatomical images are available. It integrates tightly into the SPM8 batch system within the Diffusion Toolbox. The resulting normalised images can be used for voxelwise or multivariate analyses in any of the common analysis packages for VBM. This toolbox may therefore help to standardize the FA-VBS normalisation step.