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Abstract #1649

Cerebrospinal Fluid as an Internal Quality Control Marker

Ryan J. Bosca1,2, A.J. Kumar1, Jihong Wang1

1The University of Texas M.D. Anderson Cancer Center, Houston, TX, United States; 2The University of Texas Graduate School of Biomedical Sciences, Houston, TX, United States

Cerebrospinal fluid (CSF) is a good candidate for an internal quality control marker of diffusion tensor imaging because the diffusion properties should be close to known values and show little variation over time. The apparent diffusion coefficient (ADC) and fractional anisotropy (FA) for 174 DTI (111 at 1.5T, 63 at 3.0T) studies for 20 patients were measured. Coefficients of variation were calculated for all studies at 1.5T (4.2%, 14.2%) and 3.0T (6.2%, 19.7%) for ADC and FA values, respectively. Small variations in the ADC were observed indicating CSF as a promising candidate for an internal quality control marker.