Qin Chen1,2,
Emi Takahashi3, Guangping Dai1, Ellen Grant, 1,3
1Department of Radiology, Massachusetts
General Hospital, Harvard Medical School, Martinos Center for Biomedical
Imaging, Charlestown, MA, United States; 2Department of Neurology,
West China Hospital of Sichuan Univeristy, Chengdu, Sichuan, China; 3Divison
of Newborn Medicine, Department of Medicine and Department of Radiology,
Childrens Hospital Boston, Harvard Medical School, Boston, MA, United
States
We
have shown that at postnatal day (P) 35 kittens, the degrees of myelination
varied in white matters in different brain areas (Takahashi et al.,
2009). Our purpose of current study
was to quantify the FA and ADC values on different fiber tracts in this
specific developmental phase of juvenile kitten to characterize regional
difference in degrees of maturation, and to compare these values between P35
(pediatric). Using high-resolution
diffusion spectrum imaging (DSI) tractography, we successfully imaged the
3-dimensional structure of the cortical and subcortical pathways in P35 cats.