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Abstract #1700

High Resolution in Vivo DTI of the Mouse Brain: Comparison of a Cryogenic Coil with a Room Temperature Coil

Andreas Lemke1, Patrick Heiler1, Bram Stieltjes2, Andreas Neumann3, Lothar Rudi Schad1

1Deparmtent of Computer Assisted Clinical Medicine, Heidelberg University, Mannheim, Germany; 2Deparmtent of Radiology, German Cancer Research Center, Heidelberg, Germany; 3Department of Molecular Neurobiology, German Cancer Research Center, Heidelberg, Germany

A comparison of the SNR in DTI images acquired with a cryogenic coil and a room temperature (RT) surface coil and a comparison performed by qualitative assessment of the calculated fractional anisotropy (FA)-maps at different spatial resolutions were performed on mice brain at a 9.4 T animal scanner. The SNR of the cryogenic coil was about threefold higher compared to the SNR of the RT surface coil and the quality of the FA-maps acquired with a high in plane resolution and the cryogenic coil were significantly improved compared to the RT-coil.