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Abstract #1736

Model of Blood Transport Couples Delay and Dispersion and Predicts ASL Bolus Measurements

Peter Gall1, Matthias Guether2,3, Valerij Kiselev1

1Medical Physics, University Hospital Freiburg, Freiburg, Germany; 2Fraunhofer MEVIS, Institute for Medical Image Computing, Bremen; 3Faculty for Physics and Electrical Engineering, University Bremen, Bremen, Germany

The properties of the blood transport through the brain vasculature is of fundamental interest for the diagnosis of cerebral diseases and therefore of particular interest for the associated imaging modalities in MRI such as DSC perfusion or ASL. In this work a model for a vascular tree together with laws of laminar flow are used to describe the blood transport through early branches of the vascular tree. This description is in excellent agreement with data measured using ASL.