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Abstract #1746

Improving the Spatial Resolution of 3D GRASE ASL

Emma Louise Hall1, Penny A. Gowland1, Susan T. Francis1

1Sir Peter Mansfield Magnetic Resonance Centre, University of Nottingham, Nottingham, Nottinghamshire, United Kingdom

3D-GRASE has been used with ASL but generally at coarse in-plane resolution to reduce off-resonance phase errors, and limited slice resolution to reduce through slice decay and blurring. Here we assess the use of parallel imaging combined with multi-shot acquisition and outer volume suppression (OVS) to reduce the inter-RF spacing in 3D-GRASE, allowing the acquisition of 3D-GRASE ASL data with improved spatial resolution at 3T. OVS 3D-GRASE is applied to a functional paradigm to study visual activity.