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Abstract #1773

Dynamic MR Angiography and Microvascular Flow Imaging with High Temporal Resolution Using TrueFISP Based Spin Tagging with Alternating Radiofrequency (TrueSTAR)

Lirong Yan1, Yan Zhuo1, Jing An2, Jiongjiong Wang3

1Institute of Biophysics, Chinese Academy of Sciences, Beijing, China; 2Siemens Mindit Magnetic Resonance, Siemens Healthcare, MR Collaboration NE Asia, Shenzhen, China; 3Department of Radiology, University of Pennsylvania, Philadelphia, PA, United States

In the present study, we present a novel technique termed TrueFISP based Spin Tagging with Alternating Radiofrequency (TrueSTAR) for both time-resolved 4-D MR angiography (MRA) and dynamic microvascular flow (perfusion) imaging. We demonstrate that TrueSTAR is able to delineate the dynamic filling of cerebrovasculature with a spatial resolution of 1x1x1mm3 and a temporal resolution of 50ms. Dynamic microvascular flow imaging using TrueSTAR is able to follow hemodynamic changes during visual cortex activation every 85ms.