Johannes Riegler1,2, Jack A. Wells1,
Panagiotis Kyrtatos1, Anthony N. Price1, Mark F.
Lythgoe1
1Centre for Advanced Biomedical Imaging
(CABI), Department of Medicine and Institute of Child Health, University
College London (UCL), London, United Kingdom; 2Centre for
Mathematics and Physics in the Life Sciences and Experimental Biology
(CoMPLEX), UCL, London, United Kingdom
Targeted
delivery of cells or drugs is a technique that could increase the efficacy of
medical treatments. One possibility for that is using magnetic fields to drag
labelled entities to the site of interest. MRI systems are particular
interesing for this purpose due to their ability to generate uniform magnetic
field gradients across the whole body. We demonstrated the feasibility of
steering magnetically labelled cells to one exit tube of a bifurcation
phantom by applying MR imaging gradients. This technique could potentially be
used for localised cell delivery in the vascular system.
Keywords