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Abstract #1919

3D δR2 Microscopy MRA with a New Blood Pool Contrast Agent: A Comparison with Resovist

Chien-Yuan Lin1, Si-Han Wu2, Ming-Huang Lin1, Yann Hung2, Chung-Yuan Mou2, Chen Chang1

1Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan; 2Department of Chemistry, National Taiwan University, Taipei, Taiwan

We have recently developed a new blood pool contrast agent (Fe3O4@SiO2/PEG) which possesses higher transverse relaxivity and long intravascular half-life. This study was aimed to assess the ability of Fe3O4@SiO2/PEG to improve high-resolution magnetic resonance angiography in visualizing cerebral microvasculature.