Shelton D. Caruthers1, Angana Senpan1,
Dipanjan Pan1, Grace Hu1, Samuel A. Wickline1,
Gregory M. Lanza1
1C-TRAIN,
Iron
oxide nanoparticles have been extensively used for nontargeted and targeted
imaging applications based upon highly sensitive T2* imaging properties,
which typically result in negative contrast effects. Colloidal Iron Oxide Nanoparticles offer
both traditional T2* detection and T1 weighted "hot spot"
detection. This work explores the
mechanisms for improving this T1 detectability.
Keywords