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Abstract #1990

Semi-Automatic Brain Ventricle Segmentation Using Partial Volume Fraction Calculation of CSF Based on Quantitative MRI

J. B.M. Warntjes1,2, J. West1,3, R. Birgander4, P. Lundberg5

1Center for Medical Imaging Science and Visualization (CMIV), Linkping, Sweden; 2Department of Medicine and Health, Division of Clinical Physiology, Linkping, Sweden; 3, Department of Medicine and Health, Division of Radiation Physics, Linkping, Sweden; 4Department of Radiology (NUS), Department of Radiation Sciences, Ume, Sweden; 5Department of Medicine and Health, Division of radiation physics, Linkping, Sweden

A method is described to measure the partial volume fraction of cerebrospinal fluid for each voxel in a complete brain volume within a scan time of 5 to 6 minutes, based on quantification of the relaxation rates R1 and R2 and proton density. This measurement allows to accurately segment the brains ventricular system independent of image resolution and without user-dependent image thresholding.