J. B.M. Warntjes1,2, J. West1,3, R. Birgander4, P. Lundberg5
1Center for Medical Imaging Science and Visualization (CMIV), Linkping, Sweden; 2Department of Medicine and Health, Division of Clinical Physiology, Linkping, Sweden; 3, Department of Medicine and Health, Division of Radiation Physics, Linkping, Sweden; 4Department of Radiology (NUS), Department of Radiation Sciences, Ume, Sweden; 5Department of Medicine and Health, Division of radiation physics, Linkping, Sweden
A method is described to measure the partial volume fraction of cerebrospinal fluid for each voxel in a complete brain volume within a scan time of 5 to 6 minutes, based on quantification of the relaxation rates R1 and R2 and proton density. This measurement allows to accurately segment the brains ventricular system independent of image resolution and without user-dependent image thresholding.