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Abstract #2015

Correlations Between Semantic Priming, Word Recognition and Gray Matter Density

Katie McMahon1, Anthony Angwin2, Anna Holmes3, Shiree Heath3, Sophie Van Hees3, David Copland, 2,3

1Centre for Magnetic Resonance, University of Queensland, Brisbane, Queensland, Australia; 2School of Health and Rehabilitation Sciences, University of Queensland, Australia; 3UQ Centre for Clinical Research, University of Queensland, Australia

A normal elderly cohort was examined with MRI and a lexical access/semantic priming task. The priming effect (semantically related vs unrelated prime-target pairs), and the word (semantic + unrelated response times) versus non-word targets were calculated. These variables were covaried with the individual subjects high resolution MRI images, to investigate any possible structural dependencies. Structures of areas associated with attentional and semantic priming networks were significant when compared against non-word responses, and areas of conceptual object knowledge and familiarity when compared with the priming effect.