Colleen
Dockstader1,2, William Gaetz3, Conrad Rockel1,
Donald Mabbott1
1Dept of Psychology/Division of
Haemotology/Oncology, The Hospital for Sick Children, Toronto, ON, Canada; 2Dept
of Anaesthesia and Pain Medicine, The Hospital for Sick Children, Toronto,
ON, Canada; 3Biomagnetic Imaging Laboratory, Children's Hospital
of Phiadelphia, Philadelphia, PA, United States
We
investigated age-related changes in the latency of the P100m visual response
in occipital cortex and the biophysical properties of white matter in eleven
healthy children to determine the impact of white matter growth on the
maturation of neuronal signaling. Using TBSS, we found a significant
relationship between FA and P100m latency in the dorsal processing stream.
The latency of the P100m was inversely related to FA and positively related
to age. Our findings suggest that
simple measures of evoked latency on a visuomotor-attention task reflects
dorsal stream integrity that is related to stage of cortical maturation in
healthy children.