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Abstract #2041

Optimisation of Fast Quantitative T2 Imaging of the Premature Brain: A Fantom Study

Laetitia Maurin1,2, Dominique Sirinelli2, Jean Philippe Cottier, 1,3, Laurent Barantin1,2

1NMR Department, UMR Inserm U 930 - CNRS ERL 3106 - Universit Franois Rabelais de Tours, TOURS, France; 2Pediatric Radiology, CHRU de TOURS, TOURS, France; 3Neuroradiology, CHRU de TOURS, TOURS, France

The aim of this work was to optimize and compare different T2 sequences so we could find one suitable for quantitative study of premature newborn brain. Four sequences were tested. After mathematical correction, T2 values found for each sequence were comparable to those calculated by the reference sequence. We choose the SSFSE sequence for premature T2 maps due to its duration. This sequence was optimized in order to decrease final acquisition time. This work allowed us to create a sequence, SSFSE 4 echoes, reliable and reproducible to calculate pediatric neurologic T2 maps with duration suitable for routine clinical practice.