Ericka L. Fink1,2, Patrick M. Kochanek1,2,
Ashok Panigrahy3, Fernando E. Boada4,5
1Critical Care Medicine, Children's
Hospital of Pittsburgh of UPMC, Pittsburgh, PA, United States; 2Safar
Center for Resuscitation Research, Pittsburgh, PA, United States; 3Radiology,
Children's Hospital of Pittsburgh of UPMC, Pittsburgh, PA, United States; 4Radiology,
UPMC, Pittsburgh, PA, United States; 5Magnetic Resonance Research
Center, Pittsburgh, PA, United States
In
two children with cardiac arrest, tissue sodium concentration was increased
in regions of the brain that are most vulnerable to hypoxia-ischemia and
reperfusion (basal ganglia and occipitoparietal cortex), representing prolonged
or delayed deranged brain tissue Na metabolism.