Jonathan S. Jackson1,2, Declan Chard2,
Antonia Ceccarelli1, Elisa Dell'Oglio1, Ashish Arora1,
Mohit Neema1, Rohit Bakshi1, David Miller2,
Claudia Angela Michela Wheeler-Kingshott2
1Laboratory for Neuroimaging Research,
Brigham & Women's Hospital, Harvard Medical School, Brookline, MA, United
States; 2Department of Neuroinflammation, UCL Institute of
Neurology, London, United Kingdom
Robust
lesion in-painting has been demonstrated on T1 and T2-weighted images. Many
automated algorithms rely on accurate histograms for segmentation; therefore
this approach to lesion WM correction based on the global histogram is
appropriate and strongly recommended as a pre-processing step for MS images.
Keywords