H Huang1,2, M Deng1, S F. Leung3,
Y L. Chan1, D K. Yeung1, H C. Chan1, A T.
Ahuja1, Y X. Wang1
1Department of Diagnostic Radiology and
Organ Imaging, The Chinese University of Hong Kong, Prince of Wales Hospital,
Shatin, NT, Hong Kong; 2Department of Radiology, The Shenzhen
Third Peoples Hospital, Shenzhen, China; 3Department of Clinical
Oncology, The Chinese University of Hong Kong, Prince of Wales Hospital
The
natural course of radiation induced brain injury still remains poorly
understood. Among the abnormalities white matter edema-like lesions (WML) and
contrast enhanced necrotic lesions (CEL) have been most commonly reported. It
was recently reported that radiation induced brain injury was not always an
irreversible and progressive process, but one that could show regression and
resolution. In total 22 nasopharyngeal carcinoma patients with 36 lobes
displaying WML and CEL were analysed in this study. The preliminary results
of this study suggest the development of WML and CEL tend to follow the same
pattern, and not develop in the opposite direction.