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Abstract #2187

Multi-Layer Appearance of Abscess Capsule on Post-Gd SWI Images: Effects of Filtering and Phase Mask

Ping-Hong Lai1,2, Hing-Chiu Chang3,4, Hsiao-Wen Chung4

1Department of Radiology, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan; 2School of Medicine, National Yang-Ming University, Taipei, Taiwan; 3Applied Science Laboratory, GE Healthcare Taiwan, Taipei, Taiwan; 4Institute of Biomedical Electronics and Bioinformatics, National Taiwan University, Taipei, Taiwan

SWI is a novel MR technique that exploits the magnetic susceptibility differences of various tissues, such as venous structure and iron deposition. When SWI was applied to patients with abscess, we found that, compared with homogeneous rim-enhancement on post-contrast magnitude images, the capsular portion of pyogenic brain abscess on post-contrast SWI images showed a multi-layer appearance. In this work, in order to clarify whether this multi-layer characteristic is physiological or technical in it origin, we investigate the causes of this multi-layer appearance, and use a theoretical model to simulate the multi-layer appearance upon the use of different SWI processing parameters.