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Abstract #2241

Longitudinal Assessment of Brain Damage in Hypertension Rats Using Diffusion Tensor Imaging

Chien-Yuan Lin1, Cheng-Di Chiu2,3, Ming-Huang Lin1, Wai-Mui Cheung1, Teng-Nan Lin1, Chen Chang1

1Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan; 2Graduate Institute of Medical Sciences, National Defense Medical Center, Taipei, Taiwan; 3Department of Neurosurgery, Chang-Hua Hospital, Chang-Hua, Taiwan

The elevated blood pressure is considered to be the main risk factor of stroke and is highly associated with white matter lesions. This study aimed to investigate the change of white matter microstructure under various levels of blood pressures.