Benedicte Descamps1,2, Pieter Vandemaele1,2,
Harmen Reyngoudt1,2, Karel Deblaere1,2, Luc Leybaert3,
Koen Paemeleire3,4, Eric Achten1,2
1Radiology, Ghent University, Ghent,
Belgium; 2GIfMI, Ghent, Belgium; 3Basic Medical
Sciences, Ghent University, Ghent, Belgium; 4Neurology, Ghent
University Hospital, Ghent, Belgium
In
this study, single subject net hemodynamic responses to paired stimuli from
patients with migraine without aura and controls are fitted using inverse
logit functions and compared. We demonstrate that patients with migraine
without aura do not show a decrease in amplitude of their interictal
hemodynamic response to a second stimulus in a pair with 1 second
interstimulus interval, whereas the control group shows hemodynamic
refractory effects when looking at repetitive stimuli. The finding in this
patient group may be the neurovascular correlate of the absence of
electrophysiological habituation.