Meeting Banner
Abstract #2295

Functional Connectivity in Resting State CBF Mapping in Postherpetic Neuralgia

Jing Liu1, Yue Zhang2, XiaoYing Wang3, MinYi Du4, Jue Zhang2

1Department of Radiology, Peking University First Hospital , BeiJing, China; 2College of Engineering, Peking University, BeiJing, China; 3Department of Radiology, Peking University First Hospital, BeiJing, China; 4Department of Anaesthesiology, Peking University First Hospital, BeiJing, China

Given the poor specificity and reproducibility of blood oxygenation level dependent(BOLD), we use cerebral blood flow for the first time to build resting-state networks of default mode both in patients suffering from postherpetic neuralgia and healthy subjects, and compare the two groups. The results of functional connectivity in healthy subjects showed that the areas activating were the same with the parts previously described in the literatures using BOLD. The results between-groups comparison showed that some parts were in strengthened correlation of posterior cingulate cortex in patients, such as anterior cingulated cortex and insula which are related to pain.