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Abstract #2301

Can Resting State Measurements Supplement Task Based FMRI for Presurgical Motor Cortex Mapping? a Test-Retest Reliability Study

Peter Mannfolk1, Markus Nilsson1, Ronnie Wirestam1, Freddy Sthlberg1,2, Peter Fransson3, Andreas Weibull4, Johan Olsrud1,5

1Dept. of Medical Radiation Physics, Lund University, Lund, Sweden; 2Dept. of Diagnostic Radiology, Lund University Hospital, Lund, Sweden; 3Department of Clinical Neuroscience, Stockholm Brain Institute, Karolinska Institute, Stockholm, Sweden; 4Dept. of Medical Radiation Physics, Lund University, Malm, Sweden; 5Center for Medical Imaging and Physiology, Lund University Hospital, Lund, Sweden

Clinical BOLD fMRI of children or in patients showing severe disease-related impairment can be difficult as active participation is required. Therefore, the possibility of using resting state data would be of great value. The aim of this study was to evaluate the test-retest reliability in detecting the intrinsic motor network from resting state data as compared to activation maps based on a bilateral finger tapping task. The test-retest reliability of resting state data was found to be comparable to what is seen for a typical task based fMRI-experiment within a subject. However, large differences between subjects were also found.