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Abstract #2337

A Design of Head Holder for Calculation of Susceptibility Through Multiple Orientation Sampling (COSMOS)

Hsiao-Wei Peng1, Chao-Chun Lin2,3, Yi-Jui Liu1,4, Chien-Kuo Chen1, Kuo-Fang Shao4, Wu-Chung Shen2,5, Hing-Chiu Chang6,7

1Department of Automatic Control Engineering, Feng Chia University, Taichung, Taiwan, Taiwan; 2Department of Radiology, China Medical University Hospital, Taichung, Taiwan; 3Graduate Institute of Biomedical Electronics and Bioinformatics, National Taiwan University, Taipei, Taiwan; 4Master's Program in Biomedical Informatics and Biomedical Engineering, Feng Chia University, Taichun, Taiwan; 5School of Medicine, China Medical University, Taichung, Taiwan; 6Applied Science Laboratory, GE Healthcare Taiwan, Taipei, Taiwan; 7Institute of Biomedical Electronics & Bioinformatics, National Taiwan University

We aimed to design a head holder for calculation the susceptibility through multiple orientation sampling (COSMOS). Different brain tissues with different susceptibility result in the changes of focal magnetic fileds. Quantitative susceptibility imaging of brain are obtained by measurement of the focal magnetic field changes.. It is a promising approach for exploring various brain pathological conditions. For clinical application, the challenging problem is to rotate the head of patient along the Y axis only and fix the head in the degree through the MR scan. Our results show great control of the rotation in three axes with the facilitation of head holder.