Abstract #2338

A Study Specific Brain Template in MNI Space for an Aged Population with Aortic Stenosis

Ping Wang¹, Elizabeth Strambrook², Thomas Floyd³

¹Radiology, University of Pennsylvania, Philadelphia, PA, United States; ²Anesthesiology & Critical Care, University of Pennsylvania, Philadelphia, PA, United States; ³Anesthesiology & Critical Care, and Neurology, University of Pennsylvania, Philadelphia, PA, United States

The MNI standard template is ideal for healthy subjects. To improve the accuracy of normalization and the further analysis (such as statistical analysis), we created a study specific template in MNI space for an aged population with mild to critical aortic stenosis. This study specific template is approximately in MNI template space, but accommodates some characteristics of this particular study population, especially incorporating the increased ventricular volume.