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Abstract #2348

4D Flow Measurement of Cerebrospinal Fluid Pulsation at the Craniocervical Junction and Cervical Spine and Its Clinical Potential

Alexander Christian Bunck1, Wolfram Schwindt1, Jan-Robert Krger1, Alena Jttner1, Angela Brentrup2, Barbara Fiedler3, Gerard Crelier4, Walter Heindel1, David Maintz1, Thomas Niederstadt1

1Department of Clinical Radiology, University hospital of Muenster, Muenster, Germany; 2Department of Neurosurgery, University hospital of Muenster, Muenster, Germany; 3Department of Paediatrics, University hospital of Muenster, Muenster, Germany; 4Institute for Biomedical Engineering, ETH Zurich, Zurich, Switzerland

Time resolved 3D-phase contrast imaging allows to assess cerebrospinal fluid pulsation at the craniocervical junction and cervical spine. Using state-of-the-art visualization techniques it helps to identify and differentiate between pathological and physiological cerebrospinal fluid flow pattern. As such it may add valuable information for the analysis of pathologies associated with altered cerebrospinal fluid flow like in Chiari malformations and may promote a better understanding of the underlying pathophysiology of these diseases.