Sung-Tak Hong1, Chi-Bong Choi2,
Rolf Pohmann1
1High-Field Magnetic Resonance Center ,
Max-Planck Institute for Biological Cybernetics, Tuebingen,
Baden-Wuerttemberg, Germany; 2Department of Radiology, Kyung Hee University
Medical Center, Hoekidong, Seoul, Korea, Republic of
The
effect of different anesthetic agents was investigated in the rat brain by
using in vivo 1H NMR spectroscopy. A volume-of-interest was placed in
thalamus under two different anesthesia, isoflurane and ketamine/xylazine.
The significant increase of glucose was observed in a deep ketamine/xylazine
anesthesia while additional metabolic variations on ascorbate, aspartate,
glutathione and lactate were detected.
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