Hsiao Piau Ng1,2, Marek Kubicki1,3,
Doug Terry1, Paula Pelavin1, Andrew Rausch1,
Martha E. Shenton1,3
1Psychiatry Neuroimaging Lab, Brigham
and Women's Hospital, Harvard Medical School, Boston, MA, United States; 2Singapore
Bioimaging Consortium, Agency for Science, Technology and Research,
Singapore, -, Singapore; 3Clinical Neuroscience Division, VA
Boston Healthcare System, Harvard Medical School, Brockton, MA, United States
In
this study, the connection between the bilateral STGs in normal controls (NC)
and schizophrenics (SZ) is investigated using DTI measures, namely FA, mode
and trace. The connection was obtained from whole-brain streamline
tractography using STGs white matter as ROIs. By dividing the connection into
three sub-regions (Left, Corpus Callosum and Right) and comparing the
computed DTI measures of NC and SZ, we found statistically significant
differences in mean FA and mode in the Right region, with NC having greater
values. This study paves the way for further localization of the differences
in STGs connection between NC and SZ.
Keywords