N. Jon Shah1,2, Irene Neuner1,2,
Joachim Bernhard Maria Kaffanke1, Yuliya Kupriyanova1,
Karl-Joseph Langen1, Hans Herzog1
1Institute of Neurosciences and
Medicine 4, Medical Imaging Physics, Forschungszentrum Jlich GmbH, 52425
Juelich, Germany; 2Faculty of Medicine, Department of Neurology,
RWTH Aachen University, 52074 Aachen, Germany
PET
imaging is well established for the diagnosis of brain tumours. Its metabolic
specificity delivers valuable information about the malignancy and the extent
of tumour tissue. Tumour growth forces the brain to reorganize itself to
compensate for the lost areas. It has been shown that DTI is a valuable tool
to demonstrate the plasticity of the brain and it therefore offers
information about the reorganization caused by tumour growth as well as
surgical intervention. The acquisition of trimodal PET, MP-RAGE and DTI data
on an MR-PET hybrid scanner, capable of simultaneous MR and PET, to
investigate plasticity and reorganisation in human brain tumours is
demonstrated.