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Abstract #2496

Development of Tissue Susceptibility Matched Pyrolytic Graphite Foam for Improved Frequency Selective Fat Suppression and Motion Suppression in Breast MRI

Gary Lee1, Patrick Goodwill1, Kevin Phuong2, Ben Inglis3, Brian Hargreaves4, Steven Conolly1,2

1Berkeley/UCSF Bioengineering Joint Graduate Group, Berkeley, CA, United States; 2Bioengineering, University of California - Berkeley, Berkeley, CA, United States; 3Henry J Wheeler, Jr. Brain Imaging Center, Berkeley, CA, United States; 4Radiology, Stanford University, Palo Alto, CA, United States

DCE breast MRI is emerging as the second most common diagnostic imaging modality for breast cancer, which has ~200,000 new cases and ~40,000 deaths annually. However, breast MRI still lacks adequate specificity. Magnetic susceptibility mismatches near the breast/air interface contribute to field inhomogeneities which make frequency selective fat suppression techniques more difficult. We have developed tissue susceptibility matched pyrolytic graphite foam that is lightweight, safe for patients, and compatible with embedded RF coils. PG foams may improve frequency selective fat suppression for breast MRI and provide more robust motion suppression, which may lead to improved specificity in breast cancer diagnosis.