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Abstract #2527

Exploration of Gas Flow During High Frequency Oscillated Ventilation by 19F-Gas-MRI

Janet Friedrich1, Julien Rivoire1, Alexander Wiegbert Scholz2, Maxim Terekhov1, Rainer Kbrich2, Lars Krenkel3, Claus Wagner3, Laura Maria Schreiber1

1Section of Medical Physics, Department of Diagnostic and Interventional Radiology, Johannes Gutenberg University Medical Center, Mainz, Germany; 2Department of Anesthesiology, Johannes Gutenberg University Medical Center, Mainz, Germany; 3German Aerospace Center, Gttingen, Germany

To detect convective gas flow inside the large airways during high frequency oscillated ventilation (HFOV) the fluorinated contrast gas Heptafluoropropane was used for 19F-MRI. In a first study the comparison between constant flow measurements and Computational Fluid Dynamics (CFD) simulations provided a good agreement. In a following experiment oscillated flow was applied to a lung phantom consisting of ventilation bag and long pipe. The pressure wave inside the pipe was explored point-by-point and corresponding velocities were determined. With these experiments it could be shown for the first time that flow measurement during HFOV using fluorinated contrast gas is feasible.