Jionghan Dai1, Eric Peterson2,
James H. Holmes3, Sean B. Fain1,4
1Medical Physics, University of
Wisconsin - Madison, Madison, WI, United States; 2Biomedical
Engineering, University of Wisconsin - Madison, Madison, WI, United States; 3Applied
Science Lab, GE Healthcare, Madison, WI, United States; 4Radiology,
University of Wisconsin - Madison, Madison, WI, United States
This
work seeks to provide a quantitative regional measure of gas retention in the
lung. A 3D multi-echo projection acquisition is used, accompanied with an
iterative HYPR reconstruction to provide a time resolved 3D image series.
Post exhalation images are used to generate quantitative maps of gas
retention. To summarize, this work presents potential new methods to
characterize the gas retention under forced exhalation using hyperpolarized
noble gas MRI.
Keywords