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Abstract #2619

Contrast Uptake Enhancement Patterns in Neuroendocrine Liver Metastases

Choon Hua Thng1, Tong San Koh2, Septian Hartono1, Puor Sherng Lee1, Keiko Miyazaki3, David Collins3, Martin O. Leach3, Val Lewington4, Dow-Mu Koh4

1National Cancer Centre Singapore, Singapore, Singapore; 2Nanyang Technological University, Singapore, Singapore; 3CRUK-EPSRC Cancer Imaging Centre, Institute of Cancer Research, Sutton, United Kingdom; 4Royal Marsden NHS Foundation Trust, Sutton, United Kingdom

Neuroendocrine liver metastases have been described as being hypervascular in nature, showing arterial enhancement and washout. However, other enhancement patterns have been observed in clinical practice (plateau and progressive enhancement). Three types of enhancement curves in neuroendocrine tumor was found: (1) Rapid increasing followed by decrease, (2) Rapid increasing followed by plateau, and (3) Progressively increasing. Type I pattern show higher intravascular volume (v1) compared to percentage of interstitial volume (v2). Type II and III pattern show higher v2 compared to v1. Type I pattern show higher blood flow (F) compared to Type II/III.