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Abstract #2620

Clinical Experience with Gadoxetate-Enhanced T1 Weighted Hepatobiliary Imaging in Primary Sclerosing Cholangitis

Andrzej Roman Jedynak1, Frederick Kelcz1, Alex Frydrychowicz1, Scott K. Nagle1,2, Scott B. Reeder1,3

1Radiology, University of Wisconsin, Madison, WI, United States; 2Radiology, Middleton Veterans Affairs (VA) Hospital, Madison, WI, United States; 3Medical Physics, University of Wisconsin, Madison, WI, United States

Primary sclerosing cholangitis (PSC) is a chronic inflammatory condition of extra- and intra-hepatic biliary ducts. In our clinical practice we routinely use the combination of high resolution gadoxetate-enhanced T1-MRC and heavily T2-weighted MRCP for the evaluation of PSC. This work set out to validate the clinical diagnostic utility of adding high-resolution 3D T1-weighted gadoxetate-enhanced hepatobiliary phase MRC to 3D T2 weighted MRCP. Preliminary results indicate that T1-MRC is an excellent adjunct to T2 MRCP that provides not only anatomical visualization of the biliary tree and associated disease but also offers useful functional/physiologic information that can be tremendously helpful in many cases.