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Abstract #2626

Qualitative and Quantitative Evaluation of Time-Resolved Flow Analysis of Portal Venous Hemodynamics of Liver Cirrhosis Patients and Volunteers

Zoran Stankovic1, Zoltan Csatari1, Peter Deibert2, Wulf Euringer1, Wolfgang Kreisel2, Susanne Eggerking2, Philipp Blanke1, Zahra Abdullah Zadeh1, Jrgen Hennig1, Mathias Langer1, Michael Markl1

1Department of Diagnostic Radiology and Medical Physics, University Hospital Freiburg, Freiburg, Baden Wrttemberg, Germany; 2Gastroenterology, University Hospital Freiburg, Freiburg, Baden Wrttemberg, Germany

Time-resolved flow-sensitive 4D MRI permits qualitative and quantitative evaluation of portal venous hemodynamics of liver cirrhosis patients compared to volunteers. Our results demonstrate a persistent reduction of the peak velocities in the portal venous system between patients and different age group volunteers. Analysis showed significant correlation for peak and mean velocities between MRI and US measurements (r=0.53, p< 0.001) which served as reference standard. In liver cirrhosis patients 3D MR velocity mapping may be a standardized technique for evaluating flow characteristics modification, therapy monitoring or disease progression.