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Abstract #2632

Quantification of Adipose Tissue Depots in the Obese Thigh During Weight Loss Using Dixon Method

Curtis L. Johnson1, Mina C. Mojtahedi2, Diego Hernando3,4, Dimitrios C. Karampinos1,4, Matthew P. Thorpe2, Danchin Chen1, Ellen M. Evans2,5, John G. Georgiadis1,4

1Mechanical Science and Engineering Department, University of Illinois at Urbana-Champaign, Urbana, IL, United States; 2Division of Nutritional Sciences, University of Illinois at Urbana-Champaign, Urbana, IL, United States; 3Electrical and Computer Engineering Department, University of Illinois at Urbana-Champaign, Urbana, IL, United States; 4Beckman Institute for Advanced Science and Technology, University of Illinois at Urbana-Champaign, Urbana, IL, United States; 5Department of Kinesiology and Community Health, University of Illinois at Urbana-Champaign, Urbana, IL, United States


MRI was used before and after a weight loss intervention investigating the effect of diet on body composition in obese, older women to quantify changes in adiposity in the thigh. A two-point Dixon method was used to separate fat and water images in order to quantify subcutaneous, intermuscular, and intramuscular fat as well as muscle in the thigh before and after weight loss for two groups of subjects, one taking a protein supplement and the other taking a carbohydrate for control. Results showed greater loss of adipose tissue and retention of muscle for the protein group compared to the control.

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