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Abstract #2643

Comparison of Two Strategies to Improve Quality of in Vivo 1H MR Spectra in the Presence of Motion

Michael Germuska1, Jian Xu2, Martin Leach1, Geoffrey Payne1

1CR-UK and EPSRC Cancer Imaging Centre, Institute of Cancer Research and Royal Marsden Hospital, Sutton, London, United Kingdom; 2Siemens Healthcare U.S., New York, NY, United States

In vivo 1H MR spectroscopy has proved valuable for evaluating tumours. However, acquisition of spectra in the abdomen is complicated by respiratory motion. The motion degrades the spectral quality by phase and frequency distortions and by modification of the PSF. We compared two approaches to combat motion in liver spectroscopy. The first utilises a post-processing approach to correct phase and frequency distortions, the second employs prospective gating when acquiring the data. Both techniques showed an improvement in linewidth and SNR compared to free-breathing acquisitions. The post-processing methodology showed an advantage in SNR due to the increased number of signal averages.