Rexford D. Newbould1,
1GSK Clinical Imaging Centre,
Dynamic
contrast enhanced perfusion measurement (DCE) is hampered in the body at
higher field strengths such as 3T by the large spread of achieved flipangles
across the volume of interest. In DCE,
it is common to measure the change in voxel T1 using a variable flipangle
spoiled gradient echo sequence, in order to quantify contrast agent
concentration. The extreme variation
in achieved flip angle at 3T in the body has precluded accurate
quantification. Here, B1 mapping using
the saturated double angle method is performed rapidly in the same locations
as the dynamic scan, in order to correctly estimate T1 values.
Keywords