Peter Edward Thelwall1,
1Newcastle Magnetic Resonance Centre,
Newcastle University, Newcastle upon Tyne, United Kingdom; 2Institute
of Cellular Medicine, Newcastle University, Newcastle upon Tyne, United
Kingdom
We
have applied MR imaging methods to diabetic kidney disease by investigating
the differences in kidney structure, blood flow and oxygenation between
volunteers with Type 1 diabetes with and without diabetic nephropathy, and in
non-diabetic control subjects. We hypothesised that early changes in kidney
structure and function caused by diabetic nephropathy could be identified by
altered renal structure, blood flow, and changes in oxygenation on water
loading. Differences in renal artery flux were observed between volunteer
groups.
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