Mark Stephen Dobbs1,2, Neil Woodhouse3,
Geoff J.M Parker1,2, Josephine H. Naish1,2
1Imaging Science and Biomedical Engineering,
The University of Manchester, Manchester, Greater Manchester, United Kingdom;
2The University of Manchester Biomedical Imaging Institute,
Manchester, Greater Manchester, United Kingdom; 3AstraZeneca,
Manchester, Greater Manchester, United Kingdom
ASL
has been applied extensively in the brain, but there has been increasing
interest in applying ASL to the kidneys, particularly as a result of concerns
over the link between contrast agents and NSF. Currently, most human
renal-ASL has been performed using a single inversion time, and applying a
simple model for quantification. In this abstract we aim to demonstrate the
feasibility of applying the Buxton model, at 3T, using a STAR based labelling
technique and a free breathing approach. Here, we demonstrate the
practicality of fitting for arrival time, producing high quality parametric
output.