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Abstract #2714

Evaluation of Diffusion MR as a Biomarker for Nanoparticle Therapy Response in Lymphoma

Thomas Sheung Chee Ng1,2, Daniel Procissi1, Hargun Sohi1, Andrew A. Raubitschek3, Russell E. Jacobs1

1California Institute of Technology, Pasadena, CA, United States; 2University of Southern California, Los Angeles, CA, United States; 3Beckman Institute, City of Hope, Duarte, CA, United States

IT-101 is a novel nanoparticle therapy that specifically targets the tumor mass. We evaluated whether diffusion MR is sensitive to early IT-101 response in a mouse model of lymphoma.